A System-on-Chip Assay for Bilirubin Levels Measurement in Whole Blood

Bilirubin (BR) is clinically confirmed as a biomarker for liver health and used to assess the prognosis of cirrhosis. Optical chemical methods have been utilized blood BR biosensing. While optical offer real-time monitoring are handy immune infection, measurements may not be practical due instrument complexity space requirements. This study investigated dual-wavelength (DWL) technique estimation using system-on-chip (SoC). The SoC includes an module with blue (455 nm) green (530 LEDs which were DWL measurement. Porcine was surrogate human levels kept within pathophysiological ranges projected from healthy individuals (<1.2 mg/dL) cirrhotic patients (up 50 mg/dL). Our findings show high sensitivity in blood. lays groundwork point-of-care testing levels, primarily hyperbilirubinemia infants adults out homes or in-community settings.